重组人干扰素a-2b

干扰素（IFN）是一个具有*抗病毒、抗增殖和免疫调节特性的细胞因子家族，根据其对细胞表面受体的结合特异性进行分类。在和小鼠基因组中发现了十几种密切相关的IFN-α亚型，每种亚型共享约80%的氨基酸（aa）序列同源性。IFNA2、IFNA2a、IFNA2b和IFNA2c有几种变体，它们只相差几个点突变。成熟人IFNA2b的胞外结构域（ECD）与小鼠IFNA2具有59%的aa序列同一性。

(纯度) Purity

≥95%, by SDS-PAGE (under reducing (R) & Non-reducing conditions, visualized by Coomassie staining).

(内毒素) Endotoxin

≤10 EU/mg by the LAL method.

(生物活性) Bioactivity

Measured in a VSV inhibition assay with Wish cells. The ED50 this effect is ≤100 pg/mL, corresponding to a specific bioactivity is ≥2 ×108 units/mg.

(种属) Species

Human

(表达系统) Expression System

CHO

(预测分子量大小) Mol. Weight

19.2 kDa

(表达区间) Expression Region

Cys24-Glu188

(标签) Tag Info

Tag free

(剂型) Formulation

Lyophilized

(溶液) Buffer

PBS, 5% Mannitol and 0.01% Tween 80, pH7.4.

(规格) Size

10μg/50μg/1mg

(复溶) Reconstitution

It is recommended to redissolve in sterile deionized water.

(运输) Shipping

The product is shipped with blue ice.

(存储) Storage & Stability

36 months at -20°C to -80°C in lyophilized state;

6 months at -20°C to -80°C under sterile conditions after reconstitution;

7-10 days at 2°C to 8°C under sterile conditions after reconstitution;

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.‌

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