重组人粒细胞刺激因子

Granulocyte colony-stimulating factor (G-CSF) 是一种由免疫系统细胞，成纤维细胞和内皮细胞分泌的糖蛋白，是造血和内皮前体细胞的细胞因子。G-CSF 刺激骨髓中成熟的祖细胞分化为粒细胞，巨噬细胞和 T 细胞。G-CSF 还能够通过增加 PI3K/Akt 通路的磷酸化为中枢神经元提供神经保护，并调节癌症中的上皮到间质转化。

(纯度) Purity

≥95%, by SDS-PAGE (under reducing (R) & Non-reducing conditions, visualized by Coomassie staining).

(内毒素) Endotoxin

≤10 EU/mg by the LAL method.

(生物活性) Bioactivity

The bioactivity is determined by the dose-dependent proliferation of murine NFS-60 cells is ＜ 0.5 ng/mL, corresponding to a specificBioactivity of ≥ 1 x 107 units/mg.

(种属) Species

Human

(表达系统) Expression System

CHO

(预测分子量大小) Mol. Weight

18.7 kDa

(表达区间) Expression Region

Thr31-Pro204

(标签) Tag Info

Tag free

(剂型) Formulation

Lyophilized

(溶液) Buffer

PBS, 5% Mannitol and 0.01% Tween 80, pH7.4.

(规格) Size

10μg/50μg/1mg

(复溶) Reconstitution

It is recommended to redissolve in sterile deionized water.

(运输) Shipping

The product is shipped with blue ice.

(存储) Storage & Stability

36 months at -20°C to -80°C in lyophilized state;

6 months at -20°C to -80°C under sterile conditions after reconstitution;

7-10 days at 2°C to 8°C under sterile conditions after reconstitution;

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.‌

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