热灭活大肠杆菌O145:H2阳性对照
热灭活大肠杆菌O145:H2阳性对照
热灭活大肠杆菌O145:H2阳性对照

美国Seracare热灭活大肠杆菌O145:H2阳性对照

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广州健仑生物科技有限公司

广州健仑生物科技有限公司

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美国Seracare热灭活大肠杆菌O145:H2阳性对照 热灭活大肠杆菌O145:H2质控品 抗原抗体需要了解美国Seracare的产品可以,本对照品由广州健仑生物供应。

详细介绍

美国Seracare热灭活大肠杆菌O145:H2阳性对照

广州健仑生物科技有限公司

广州健仑长期供应各种生物原料,主要代理品牌:美国Seracare、西班牙Certest、美国Fuller等等。

主要产品包括各种标准品、阳性对照品、阳性质控品、单克隆抗原抗体

其中常见的有:弓形虫病、西尼罗河病毒、类风湿因子、疟疾、麻疹、莱姆病、百日咳杆菌、大肠杆菌、鼠伤寒沙门氏菌、李斯特菌等阳性对照品。

美国Seracare热灭活大肠杆菌O145:H2阳性对照

我司还提供其它进口或国产试剂盒:登革热、疟疾、流感、A链球菌、合胞病毒、腮病毒、乙脑、寨卡、黄热病、基孔肯雅热、克锥虫病、违禁品滥用、肺炎球菌、军团菌、化妆品检测、食品安全检测等试剂盒以及日本生研细菌分型诊断血清、德国SiFin诊断血清、丹麦SSI诊断血清等产品。

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Seracare产品介绍】

货号

中文名称

英文名称

JL-SC001

鼠伤寒沙门氏菌阳性对照

Salmonella typhimurium Positive Control

JL-SC002

志贺氏菌属阳性对照

Shigella Species Positive Control

JL-SC003

弧菌属阳性对照

Vibrio Species Positive Control

JL-SC004

军团菌嗜肺军团菌阳性对照

Legionella pneumophila Positive Control

JL-SC005

BacTrace®金黄色葡萄球菌阳性对照

BacTrace® Staphylococcus aureus Positive Control

JL-SC006

Bactrace®化脓性链球菌阳性对照

BacTrace® Streptococcus pyogenes Positive Control

JL-SC007

bactrace®无乳链球菌阳性对照

BacTrace® Streptococcus agalactiae Positive Control

JL-SC008

李斯特菌属特异性阳性对照

Listeria, Genus-Specific Positive Control

JL-SC009

弯曲菌属特异性阳性对照

Campylobacter, Genus-Specific Positive Control

JL-SC010

幽门螺旋杆菌阳性对照

Helicobacter pylori Positive Control

JL-SC011

大肠杆菌O157:H7阳性对照

Escherichia coli O157:H7 Positive Control

JL-SC012

BacTrace®大肠杆菌O111:H8物种阳性对照

BacTrace® Escherichia coli O111:H8 Species Positive Control

JL-SC013

BacTrace®大肠杆菌O26:H11物种阳性对照

BacTrace® Escherichia coli O26:H11 Species Positive Control

JL-SC014

Bactrace®大肠杆菌O103:H8的阳性对照,热灭活

BacTrace® E.coli O103:H8 Positive Control, Heat-Killed

JL-SC015

Bactrace®大肠杆菌O145:H2的阳性对照,热灭活

BacTrace® E.coli O145:H2 Positive Control, Heat-Killed

JL-SC016

Bactrace®大肠杆菌O121:H19的阳性对照,热灭活

BacTrace® E.coli O121:H19 Positive Control, Heat-Killed

JL-SC017

Bactrace®大肠杆菌O45:H2的阳性对照,热灭活

BacTrace® E.coli O45:H2 Positive Control, Heat-Killed

JL-SC018

BacTrace®大肠杆菌O104:H12阳性对照

BacTrace® Escherichia coli O104:H12 Positive Control

JL-SC019

BacTrace®大肠杆菌O91阳性对照

BacTrace® Escherichia coli O91 Positive Control

JL-SC020

鲑肾杆菌阳性对照

Renibacterium salmoninarum Positive Control

美国Seracare

数十年前,科学家们就已经学会了将一连串的DNA碱基转变为蛋白质氨基酸的基本遗传密码读取细胞。但是十多年来,他们还在试图破译嵌入在生物体基因组中更为复杂的密码:组蛋白密码。组蛋白是指在染色体中DNA缠绕的一类特殊蛋白。采用化学方法以各种方式调整组蛋白就可以调节(上调或是下调)基因的活性。
例如,细胞通过将三个甲基附着到H3组蛋白的一个特异位点上就可以关闭一些基因。而将三个甲基附着到另一个H3位点上,这种称之为H3K4me3的修饰则可对基因表达发挥正调控效应。细胞通常将H3K4me3标记添加到基因组小段区域的组蛋白上,然而现在研究人员注意到这种标记有时可以遍布于更大的区域,修饰大量的组蛋白。
为了查明这些大H3K4me3标记区域是否在组蛋白密码中传送了一种信息,斯坦福大学的分子遗传学家Anne Brunet和同事们在20多种不同的细胞类型中追踪了它们的存在。他们发现在不同的细胞类型中广大的H3K4me3区域标记了不同的基因。由此,研究人员认识到根据广大H3K4me3区域的染色质定位,他们就可以将肝细胞与肌肉细胞或肾细胞区分开来。此外,他们还注意到这些H3K4me3区域往往标记的是对细胞功能至关重要,或是帮助细胞确立*身份的一些基因。例如,在胚胎干细胞中它们出现在控制细胞特化能力的一些基因上。
研究人员在成体神经祖细胞中利用rnai技术,进一步证实这些标记表明了细胞的身份。当他们利用RNAi来下调携带大块H3K4me3标记的一些基因时,发现损害了细胞增殖和生成神经元的能力。而当研究人员沉默只有短H3K4me3标记区域或根本没有H3K4me3区域的基因时,祖细胞仍然正常分裂。换句话说,大H3K4me3标记区域的存在有可能帮助了细胞终身维持身份。尽管细胞利用了几种方法来确立它们的身份,“我们发现了一种新的标记,”Brunet说。
凯斯西储大学表观基因组学家Peter Scacheri对这篇论文给予了高度的评价:“我认为它将震动研究团体。尽管许多其他的科学家们一直在研究H3K4me3标记,认为这一标记可以区分所有的细胞类型这一观点真是令人震惊。检测这些标记非常容易,因此这一研究发现使得人们能够快速地鉴别一些细胞类型,在诸如癌症诊断等情况下它将派上用场。”

美国Seracare

我司还提供其它进口或国产试剂盒:登革热、疟疾、流感、A链球菌、合胞病毒、腮病毒、乙脑、寨卡、黄热病、基孔肯雅热、克锥虫病、违禁品滥用、肺炎球菌、军团菌、食品安全、化妆品检测、药物滥用检测等试剂盒以及日本生研细菌分型诊断血清、德国SiFin诊断血清、丹麦SSI诊断血清等产品。

想了解更多的产品及服务请扫描下方二维码:

【公司名称】 广州健仑生物科技有限公司
【市场部】    杨永汉

【】 
【腾讯  】 2042552662
【公司地址】 广州清华科技园创新基地番禺石楼镇创启路63号二期2幢101-103室

Decades ago, scientists learned to read cells from the basic genetic code that transforms a series of DNA bases into protein amino acids. But for more than a decade, they are still trying to decipher the more complex passwords embedded in the genome of the organism: the histone code. Histone is a type of special protein that is entangled in the DNA of a chromosome. The chemical regulation of histones in a variety of ways can regulate (up-regulate or down-regulate) the activity of a gene.
For example, cells can turn off some genes by attaching three methyls to a specific site on H3 histones. While attaching three methyls to another H3 site, this modification, called H3K4me3, can exert a positive regulatory effect on gene expression. Cells typically add the H3K4me3 marker to histones in small regions of the genome, but now researchers have noticed that such markers can sometimes modify large quantities of histones throughout a larger area.
To see if these large H3K4me3 marker regions send a message in histone codes, Anne Brunet, a molecular geneticist at Stanford University, and colleagues track their presence in more than 20 different cell types. They found that a wide range of H3K4me3 regions marked different genes in different cell types. As a result, the researchers realized that based on the chromatin localization of the vast H3K4me3 region, they could distinguish hepatocytes from muscle cells or kidney cells. In addition, they also noted that these H3K4me3 regions often tagged genes that are crucial to cellular function or help cells establish unique identities. For example, in embryonic stem cells they appear on a few genes that control the cell's specialized ability.
Using rnai technology in adult neural progenitors, the researchers further confirmed that these markers indicate cellular identity. When they used RNAi to down-regulate a few genes that carry large H3K4me3 markers, they were found to impair the ability of cells to proliferate and produce neurons. When researchers silenced only the short H3K4me3-tagged region or no H3K4me3 region, the progenitor cells normally split. In other words, the presence of a large H3K4me3 tagged region may have helped the cell stay alive for life. Although the cells utilize several ways to establish their identity, "we found a new marker," Brunet said.
Peter Scacheri, an epigenomologist at Case Western Reserve University, commented highly on the paper: "I think it will shake the research community, and while many other scientists have been studying the H3K4me3 marker, they think the marker distinguishes all Of the cell types are so alarming.The detection of these markers is so easy that the study found that it enabled people to quickly identify a few cell types that would be useful in cases such as cancer diagnosis.

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