Anti-Vimentin抗体,波形蛋白抗体
时间:2014-07-10 阅读:293
Anti-Vimentin抗体,波形蛋白抗体相关产品:
Anti-CMKLR1/CHEMR23(Chemokine receptor-like 1) 趋化样因子受体1抗体
Anti-MTLC (myc target 1) 致癌基因抗体
Anti-phospho C-Myc(pThr58/pSer62) 抗磷酸化致癌基因C-Myc抗体
Anti-phospho C-Met/HGFR(pTyr1365) 磷酸化原癌基因c-Met抗体
Anti-c-Myc tag c-Myc tag标签抗体
Anti-AU5 tag AU5 tag标签抗体
Anti-AU1 tag 抗AU1 tag标签抗体
Glu-Glu Tag Anti-Glu-Glu Tag
Anti-E Tag 抗E Tag抗体
Anti-CNGA2(Cyclic Nucleotide Gated Cation Alpha 2) 抗环核苷酸阳离子通道蛋白α2抗体
Anti-CANX(calnexin) 抗钙连蛋白抗体
Anti-CNP/CNPase ( 2',3'-cyclic-nucleotide 3'-phosphodiesterase) C型钠尿肽抗体
Anti-CNR-1(Cannabinoid receptor I brain) 钙粘蛋白相关的神经受体1抗体
Anti-CNTFR α(Ciliary neurotrophic factor receptor alpha) 抗睫状神经营养因子受体α抗体
Anti-CNR-2/PCDHA 6(Cadherin-related neuronal receptor2) 钙粘蛋白相关的神经受体2抗体
Anti-Vimentin抗体,波形蛋白抗体Background: Vimentin is the major subunit protein of the intermediate filaments of mesenchymal cells. It is believed to be involved with the intracellular transport of proteins between the nucleus and plasma membrane. Vimentin has been implicated to be involved in the rate of steroid synthesis via its role as a storage network for steroidogenic cholesterol containing lipid droplets. Vimentin phosphorylation by a protein kinase causes the breakdown of intermediate filaments and activation of an ATP and myosin light chain-dependent contractile event. This results in cytoskeletal changes that facilitate the interaction of the lipid droplets within mitochondria, and subsequent transport of cholesterol to the organelles leading to an increase in steroid synthesis. Immunohistochemical staining for Vimentin is characteristic of sarcomas (of neural, muscle and fibroblast origin) compared with carcinomas which are generally negative. Melanomas, lymphomas and vascular tumors may all stain for Vimentin. Vimentin antibodies are thus of value in the differential diagnosis of undifferentiated neoplasms and malignant tumors. They are generally used with a panel of other antibodies including those recognizing cytokeratins, lymphoid markers, S100, desmin and neurofilaments.
Anti-Vimentin抗体,波形蛋白抗体Application :
Western blotting 1:100-500
Immunohistochemistry 1:100-500
IF=1:100-500
ELISA 1:500-1000
IP=1:20-100
IHC-P=1:100-500 IHC-F=1:100-500
Optimal working dilutions must be determined by the end user.
:021 60340850 021 60340830 021 60340820
客服 :372584443 1091953152 827774711