Cat. Number:  Rs- 2496R

 

Quantity size:  0.1ml （dilute with pH 7.4    0.01 M PBS or diluent of antibody）

 

Background: CD43 is one of the major glycoproteins of thymocytes and T lymphocytes, it plays a role in the physicochemical properties of the T cell surface and in lectin binding. CD43 presents carbohydrate ligands to selectins. It has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. The antigen is a counter receptor for SN/Siglec1. During T cell activation CD43 is actively removed from the T cell antigen presenting cell contact site suggesting a negative regulatory role in adaptive immune response. CD43 is expressed by the majority of leucocytes, with the exception of most B cells. However CD43 expression is seen in some cases of B cell lymphocytic lymphoma and centrocytic lymphoma.

 

Anti-CD43 抗体说明书Specificity:      ·anti- CD43 is a rabbit monoclonal antibody unconjugated

                ·specific for CD43 of rat  

                ·epitope mapping near the amino terminus of CD43 of  

                · use for western blotting, elisa, immunoprecipitation    

· Protein A affinity chromatography purification, purity :>95%

· Isotype: IgG

· mol wt: 82kDa

 

Anti-CD43 抗体说明书Application:     · Western blotting: 1:100-500

· Immunohistochemistry: 1:100-500

· ELISA: 1:500-1000

· Optimal working dilutions must be determined by the end user.

 

 

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.