其他品牌 品牌
生产厂家厂商性质
广州市所在地
其它名称:免疫球蛋白IgG4蛋白,IgG4 protein,IgG4抗原
货号:G7043
种类:抗原
应用:Standard
特异性:Human IgG4
来源:重组蛋白
存贮:-20℃
免疫球蛋白IgG,由B淋巴细胞激活的浆细胞分泌产生。是人血清中丰富的蛋白质之一。IgG又分为四种亚型(IgG1,IgG2,IgG3,IgG4),最主要的是IgG1,而IgG4占总IgG的5%左右。
产品说明
IgG1 immunoglobulin is most prevalent (>50%) and the IgG4 variety constitutes less than 5%. IgG4 has disulfide bonds linking the heavy chains unsteadily, allowing their separation and forming 2 antigen-binding sites, so that the bispecific antibody is asymmetric with an unclear in vivo role. IgG4 interacts with the Fc portion of IgG1–3 and not through the Fab-Fc, as occurs with other immunoglobulins, and has rheumatoid factor activity. Therefore, IgG4 has little or no cross-reactivity between antigens and rarely forms immune complexes having no complement activation capacity
This product is for research use only. It is not intended for diagnostic or therapeutic use.
IgG4抗原注意事项:
1.本品为蛋白质制剂,未添加任何防腐剂和保护剂,在2-8℃可短期保存
2.本品作为诊断试剂原辅材料,不得直接用于诊断或治疗。