Biotium is a unique biotechnology company in the field of fluorescence technology, located in Bay Area, California, USA - the world's leading biotechnology center. The company has been committed to the development and production of fluorescent indicators and other special biochemical products for biomedical research. Its products are widely used in many fields such as cell biology, proteomics, molecular biology, immunology, microbiology, diagnostics, biochemistry, neuroscience, blood flow detection and large-scale drug screening. Biotium has many patented products, including the widely used real-time PCR quantitative fluorescent dye EvaGreen, the epoch-making gel nucleic acid dyes GelRed and GelGreen, as well as the latest Cheetah Taq hot start enzyme and CF series protein labeling dyes.

Currently, Biotium has licensed many of its patented technologies to major international biotechnology companies, including Agilent, BD Biosciences, Biogen, BioRad, EMD Millipore, Illumina, PerkinElmer, Qiagen, Roche, Sartorius AG, Sigma Aldrich, Thermo Fisher Scientific, and others. BTProbes was established in China in 2007 by Biotium, a well-known fluorescence reagent company in the United States. It is a high-tech enterprise specializing in the research and development of biological fluorescence reagents and a long-term supplier to multiple European and American companies. Its products are widely used in various fields of life sciences. At present, Baotian can provide over 100 popular fluorescent proteins (PE, APC), other fluorescent materials (FITC), and PCR fluorescent materials (5-FAM, 6-TAMRA).

Biotium主要产品线有：

蛋白抗体标记

抗体标记试剂盒：CF系列染料，生物-素，FITC，DIG； 以及针对于小配体(SNAP-tag, CLIP-tag, HaloTag)，纳米抗体，用于小动物体内成像的标记试剂盒；

抗体：一抗，CF染料和HRP标记全种属的二抗；

酪胺信号放大试剂：Tyramide(TSA)；

超40种全谱系荧光CF系列染料： 颜色涵盖从紫色到近红外，适用于STORM, STED, SIM, 2-photon, TIRF等高分辨率显微镜；

Biotium分子相关产品：

核酸凝胶染料：GelRed，GelGreen，PAGE GELRED，DNAZURE，EMBER500 RNA PRESTAIN，Oxazole Gold (SYBR Gold) $Thiazole Green (SYBR Green I).

PCR和DNA扩增：EvaGreen染料，各种qPCRMaster Mix，dNTPs, ROX参比染料，化学修饰的热启动Taq酶，核酸聚合酶活性检测试剂盒；

核酸提取&定量试剂盒：可从FFPE样品，新鲜组织和细胞，或琼脂糖凝胶中提取DNA或者RNA；ACCUBLUE&ACCUCLEAR DNA和RNA定量试剂盒；

Biotium酶底物及检测：

酶底物：Caspase酶底物，D-荧光素钾盐/钠盐，DAB底物，BCIP，β-半乳糖苷酶底物；

检测试剂盒：MTT，XTT细胞活力检测，ATP-Glo 细胞活力检测，Firefly &Renilla 荧光素酶报告基因检测试剂盒；

Biotium细胞染色：

细胞活力&增殖&凋亡：Calcein-AM细胞活力测定，ViaFluor细胞增殖，JC-1，TMRM & TMRE，MitoView等检测线粒体膜电位，细胞毒性/活力染色，Live-or-Dye活死细胞染色，Annexin V & NucView凋亡&坏死检测；RedDot1&NucSpot细胞周期分析染料；

细胞周期：RedDot1&NucSpot细胞周期分析染料；

细胞器：细胞膜(CellBrite染料), 线粒体(MitoView染料)，溶酶体(LysoView染料)，脂滴(LipidSpot脂滴染料)，细胞骨架(ViaFluorTubulin&Actin染料)，囊泡和膜的运输，外泌体和细胞外囊泡(EV)(ExoBrite EV染料)，胞浆染色(ViaFluor和Calcein AM)，全套神经元染色解决方案(Hydrazide, SynaptoGreen & AM1-43);

细菌&真菌染色：细菌活力和革兰氏染色， Yeast Live-or-Dye酵母活死细胞染色试剂盒，酵母细胞器染色；

钙离子&其他离子指示剂：Fluo-3，Fluo-4，Fura-2，Bis-fura-2，Furaptra，Indo-1，Rhod-2，Rhod-590，氯离子探针，锌离子探针，pH探针；

分子信号检测(ROS和NO)：DAA，二氢罗丹明，H2DCFDA；

封片剂及淬灭剂：EVERBRITE系列，TRUEBLACK系列；

流式细胞相关配件：固定缓冲液，渗透缓冲液，渗透和封闭缓冲液，细胞刮刀；

Biotium蛋白质检测、定量和分析：

蛋白凝胶染料：One-Step系列

VERSABLOT 总蛋白归一化试剂盒

GLOMELT蛋白热稳定性测定试剂盒

ACCUORANGE 荧光法蛋白定量试剂盒

Biotium专注于细胞生物学、蛋白质组学、分子生物学、免疫学、微生物学、诊断学、生物化学、神经科学、血液流动检测及大规模药物筛选等众多领域。艾美捷科技是Biotium的中国代理商，为科研工作者提供优质的产品与服务。