Rabbit  Anti- FGF23劲爆*
FROM:abcam    Catalog Number : RS-5768R        

Quantity size :   0.1ml  （dilute with pH 7.4    0.01 M PBS or antibody diluent ）

Background: Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL （By similarity）. Acts directly on the parathyroid to decrease PTH secretion （By similarity）. Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization.

Subunit : Interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors （FGFs） and their receptors is increased by KL and heparan sulfate glycosaminoglycans that function as coreceptors.

pecificity :   

• Anti- FGF23 is a rabbit polyclonal antibody unconjugated               
• specific for FGF23 of  human,rat,mo,pig        
• use for western blotting,elisa,immunoprecipitation and immunohistochemistry
• Protein G affinity chromatography purification, purity :>95%
• Isotype:  IgG
• mol wt:27 kDa

Application :  

• Western blotting 1:100-500               
• Immunohistochemistry 1:100-500                
• ELISA 1:500-1000                 
• Optimal working dilutions must  be determined by the end user.

Storage:  Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The  lyophilized antibody is stable at room temperature for at least one month and for greater  than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent  of antibody, the antibody is stable for at least six weeks at 2-4 ℃

Important Note: This product as supplied is intended for research use only, not for use in  human, therapeutic or diagnostic applications.