Anti-Phospho-BRCA1(Ser1387),磷酸化乳腺癌易感基因1抗体科研

Anti-Phospho-BRCA1(Ser1387),磷酸化乳腺癌易感基因1抗体科研

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2018-05-04 17:38:53
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华瑞科研网-ELISA试剂盒

华瑞科研网-ELISA试剂盒

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Anti-Phospho-BRCA1(Ser1387),磷酸化乳腺癌易感基因1抗体科研产品介绍:

This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximay 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described. A related pseudogene, which is also located on chromosome 17, has been identified. 


与“Anti-Phospho-BRCA1(Ser1387),磷酸化乳腺癌易感基因1抗体科研”有关的产品:

Anti-CYP450(Cytochrome P450 monooxygenase)  细胞色素P450单氧化酶抗体
Anti-Cyr61/IGFBP10/CCN1(cysteine rich 61)  富半*肝素结合蛋白61抗体
Anti-CYP2E1(cytochrome P450 2E1)  抗细胞色素P450ⅡE1抗体
Anti-Cytochrome C  细胞色素 C抗体
Anti-DRD1 receptor (dopamine D1 receptor)  多巴胺受体-D1抗体
Anti-DRD2 receptor(dopamine D2 receptor)  多巴胺受体-D2抗体
Anti-DRD3 receptor(dopamine D3 receptor)  多巴胺受体-D3抗体
Anti-DAT1(dopamine transporter)  抗多巴胺相关转录因子1抗体
Anti-DRD4 receptor(Dopamine D4 Receptor )  多巴胺受体-D4抗体
Anti-DRD5 receptor(dopamine D5 receptor)  多巴胺受体-D5抗体

Anti-Phospho-BRCA1(Ser1387),磷酸化乳腺癌易感基因1抗体科研产品详情:
产品编号:HRK-12885R
产品规格: 0.1ml/0.2ml
产品别名:BRCA1 (phospho S1387); BRCA1 (phospho Ser1387); p-BRCA1 (S1387); p-BRCA1 (Ser1387); p-BRCA1 (phospho S1387); BRCA 1; BRCA1; BRCA1/BRCA2 containing complex subunit 1; BRCA1/BRCA2-containing complex, subunit 1; BRCA1_HUMAN; BRCAI; BRAC 1; BRCA 1; BRCC 1; BRCC1; Breast Cancer 1; Breast Cancer 1 Early Onset; Breast cancer type 1 susceptibility protein; Breast and ovarian cancer susceptibility protein 1; Breast Ovarian Cancer Susceptibility; IRIS; Papillary Serous Carcinoma Of The Peritoneum; PSCP; RING finger protein 53; BROVCA1; IRIS; PNCA4; PPP1R53; Protein phosphatase 1 regulatory subunit 53; RNF53; BAP1
产品价格:询价(电询或客服)
产品用途:科研实验
贮 存:   贮存于-20℃.

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小鼠蛋白激酶B(PKB)试剂盒说明书,96T/48T代测
小鼠分泌型免疫球蛋白A(sIgA)试剂盒说明书,96T/48T代测
小鼠血红素氧合酶2(HO-2)试剂盒说明书,96T/48T代测
小鼠骨胶原交联(Cr)试剂盒说明书,96T/48T代测
小鼠Ⅰ型前胶原C末端肽(CⅠCP)试剂盒说明书,96T/48T代测

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