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面议Anti-Phospho-BRCA1(Ser1387),磷酸化乳腺癌易感基因1抗体科研产品介绍:
This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximay 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described. A related pseudogene, which is also located on chromosome 17, has been identified.
与“Anti-Phospho-BRCA1(Ser1387),磷酸化乳腺癌易感基因1抗体科研”有关的产品:
Anti-CYP450(Cytochrome P450 monooxygenase) 细胞色素P450单氧化酶抗体
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Anti-Phospho-BRCA1(Ser1387),磷酸化乳腺癌易感基因1抗体科研产品详情:
产品编号:HRK-12885R
产品规格: 0.1ml/0.2ml
产品别名:BRCA1 (phospho S1387); BRCA1 (phospho Ser1387); p-BRCA1 (S1387); p-BRCA1 (Ser1387); p-BRCA1 (phospho S1387); BRCA 1; BRCA1; BRCA1/BRCA2 containing complex subunit 1; BRCA1/BRCA2-containing complex, subunit 1; BRCA1_HUMAN; BRCAI; BRAC 1; BRCA 1; BRCC 1; BRCC1; Breast Cancer 1; Breast Cancer 1 Early Onset; Breast cancer type 1 susceptibility protein; Breast and ovarian cancer susceptibility protein 1; Breast Ovarian Cancer Susceptibility; IRIS; Papillary Serous Carcinoma Of The Peritoneum; PSCP; RING finger protein 53; BROVCA1; IRIS; PNCA4; PPP1R53; Protein phosphatase 1 regulatory subunit 53; RNF53; BAP1
产品价格:询价(电询或客服)
产品用途:科研实验
贮 存: 贮存于-20℃.
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