mouse Anti- CD144标记抗体, RBITC红色 conjugated

RICKY
Catalog Number : RSF- 4310R-RBITC

Quantity size : 100ug (2mg/ml,Lyophilized. Buffer = 0.01M PBS, pH 7.4 with 10mg/ml BSA and 0.1% Sodium azide. Reconstitute with 100ul sterile distilled water. )

background:CD144标记抗体, RBITC红色 conjugated
This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008].
Function:
Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton.

Specificity : · anti- CD144 is a mouse monoclonal antibody, RBITC conjugated

· specific for anti- CD144/RBITC of rat human and mouse.

· Protein G affinity chromatography purification, purity :>95%

· Isotype: IgG CD144标记抗体, RBITC红色 conjugated

· mol wt：81kDa

Application : · FCM: 1:50-200

·IF : 1:50-1:200

· Immunocytochemistry: 1:50-1:200

· Excitation spectrum: 540 nm

· Emission spectrum: 625 nm

· Optimal working dilutions must be determined by the end user.

· protect from light.

Storage: Store at –20 ºC for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20ºC. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least two weeks at 2-4 ºC.

CD144标记抗体, RBITC红色 conjugated

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.