Nova利什曼虫检测试剂盒

利什曼虫检测试剂盒

利什曼虫leishmanioses的病原体。利什曼虫属的许多物种对人类致病性没有显示形态学差异。它们可以分化的基础上生物标准,实验分析了不同临床图片和流行病学的事实(见标签。)。
利什曼虫属Phlebotomus雌蚊的传播和Lutzomyia(白蛉?),发生在温暖地区的国家在亚洲、非洲、欧洲地中海国家和拉丁美洲。无鞭毛体阶段的寄生虫摄取的昆虫肠道的血被转换成纤细,鞭打promastigote形式,繁殖和迁移回吻。当感染白蛉再bloodmeal promastigote形式被接种到一个新主机(人类或其它脊椎动物)。
在宿主promastigotes迅速转变成无鞭毛体阶段(12 - 14小时内),然后释放过程类似胞外分泌和可以感染新的细胞。在皮肤和黏膜与皮肤的leishmanioses寄生虫一般仍局限于皮肤或皮肤和粘膜。皮肤leishmanioses病变可能持续很长一段时间,但往往自发愈合,而更倾向于破坏性变化在黏膜与皮肤的leishmanioses感染。相比之下在内脏leishmanioses有机体可以入侵整个单核吞噬系统各器官(脾、肝、淋巴结、节点、骨髓、血液单核细胞等),导致感染,没有治疗通常是致命的。

感染的诊断则需要通过:

显微镜:
测定有色Giemsa-stained涂片的病原体

血清学:
确定特定的基于ELISA-technique抗体

NovaLisa吗?婴儿利什曼虫免疫球蛋白ELISA:
NovaLisa吗?婴儿利什曼虫免疫球蛋白ELISA用于定性测定IgG-class婴儿利什曼虫抗体在人类血清或血浆(柠檬酸)。

抗原:
纯化利什曼虫抗原

具体的性能特征:

订单信息:

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Leishmania infantum

Leishmania is the causative agent of leishmanioses. The many species of the genus Leishmania pathogenic to humans do not show morphological differences. They can be differentiated on the basis of biological criteria, laboratory analyzes the different clinical pictures and epidemiological facts (see tab.). 
Leishmania are transmitted by female mosquitoes of the genera Phlebotomus and Lutzomyia (?sandflies?), that occur in warmer regions of countries in Asia, Africa, Europe (Mediterranean countries) and Latin America. The amastigote stages of the parasite ingested by the insect with a blood meal are transformed in its intestine into slender, flagellate promastigote forms, which multiply and migrate back into the proboscis. When infected sandflies take another bloodmeal the promastigote forms are inoculated into a new host (humans or other vertebrates). 
In the host the promastigotes quickly (within 12-14 hours) transform into amastigote stages, which then released in a process resembling exocytosis and can infect new cells. In cutaneous and mucocutaneous leishmanioses the parasites generally remain restricted to the skin or skin and mucosa. Cutaneous leishmanioses lesions may persist for long periods, but tend to heal spontaneously, whereas a greater tendency to destructive changes is seen in mucocutaneous leishmanioses infections. By contrast in visceral leishmanioses the organism can invade the entire mononuclear phagocytic system in various organs (spleen, liver, lymph, nodes, bone marrow, blood monocytes etc.), causing infections that are normally lethal without treatment.  

Infections may be diagnosed by:

Microscopy:      
determination of the pathogen in coloured Giemsa-stained smears

Serology:          
determination of specific antibodies based on the ELISA-technique

NovaLisa? Leishmania infantum IgG ELISA:
The NovaLisa? Leishmania infantum IgG ELISA is intended for the qualitative determination of IgG-class antibodies against Leishmania infantum in human serum or plasma (citrate).

Antigens:
Purified Leishmania antigens

Specific performance characteristics:

Order information: