检测Anti-Bacillus anthracis lethal factor抗体,炭疽杆菌致死因子

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检测Anti-Bacillus anthracis lethal factor抗体,炭疽杆菌致死因子LF抗体简单介绍：

产品别名：Anthrax lethal factor; Anthrax lethal toxin endopeptidase component; Anthrax LF; bacillus anthracis lethal factor; Lef; LF; LEF_BACAN.

产品用途：科研实验

产品编号：BYK-12564R

性 状：Lyophilized or Liquid

浓 度：1mg/1ml

亚 型：IgG

贮 存：贮存于-20℃.

此抗体本公司有单抗和多抗，可用于免疫组化（IHC），免疫印迹（WB），酶联免疫(ELISA)，IF、IP、流式细胞术等实验（可来电索取说明）

相关标记有：Alexa Fluor 350 标记、Alexa Fluor 488 标记、Alexa Fluor 555 标记、Alexa Fluor 647 标记、AP标记、APC标记、Biotin标记、Cy3标记、Cy5标记、Cy5.5标记、Cy7标记、FITC标记、Gold标记、HRP标记、PE标记、PE-Cy3标记、PE-CY5标记、PE-CY5.5标记、PE-CY7标记、RBITC标记

检测Anti-Bacillus anthracis lethal factor抗体,炭疽杆菌致死因子LF抗体产品说明：The protease enzyme Lethal Factor (LF) is one of the three proteins (LF, EF & PA) composing the anthrax toxin produced by Bacillus anthracis, a bacteria which can infect many mammalian species and that may be fatal. LF is not toxic by itself, but when associated with Protective Antigen (PA), can then gain entry to cells. Once inside the cell, LF then cleaves the N terminal of most dual specificity mitogen activated protein kinase kinases (MAPKKs or MAP2Ks) (except for MAP2K5). Cleavage invariably occurs within the N terminal proline rich region preceding the kinase domain, thus disrupting a sequence involved in directing specific protein protein interactions necessary for the assembly of signaling complexes. There may be other cytosolic targets of LF involved in cytotoxicity. The proteasome may mediate a toxic process initiated by LF in the cell cytosol involving degradation of unidentified molecules that are essential for macrophage homeostasis. This is an early step in LF intoxication, but it is downstream of the cleavage by LF of MEK1 or other putative substrates.

保存条件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
连续使用时4°C存储，保质期六个月补体C1qα链多肽抗体*存储时建议分装为10ul以上小包装-20°C存储，并避免反复冻融，保质期一年。

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